Macrene Actives, previously known as 37 Actives, contain 37 plant-derived actives in a clean, vegan, lightweight, and non-acnegenic formula to address the signs of aging with an added potent firming action. Scientifically proven and dermatologist tested to firm and tone the skin, reduce the appearance of fine lines and wrinkles, reduce the appearance of blemishes and spots, smooth skin texture, and soothe & hydrate the skin. Backed by plant science from her organic farm and lab, Dr. Macrene’s revolutionary formulas nourish the skin with clean, active ingredients for visible restoration. Organic, clinically-tested plant derivatives are hand-made in small batches in her lab to deliver results, diminish signs of aging, and protect the skin from environmental pollutants and toxins. Vegan, silicone-, paraben- and sulfate- free.